Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.010 None 1.000 1 0 2019 2019
Entrez Id: 6016
Gene Symbol: RIT1
RIT1
Q92963 Ras like without CAAX 1 Enzyme modulator 184 0.527 0.808 0.13 0.200 None 1.000 1 0 2019 2019
Entrez Id: 8216
Gene Symbol: LZTR1
LZTR1
Q8N653 leucine zipper like transcription regulator 1 152 0.547 0.808 1.0E-92 0.200 None 1.000 1 0 2018 2018
Entrez Id: 152273
Gene Symbol: FGD5
FGD5
Q6ZNL6 FYVE, RhoGEF and PH domain containing 5 Enzyme modulator 24 0.780 0.346 1.00 0.020 None 1.000 2 0 2017 2018
Entrez Id: 8879
Gene Symbol: SGPL1
SGPL1
O95470 sphingosine-1-phosphate lyase 1 85 0.597 0.731 3.6E-03 0.020 None 0.500 2 0 2017 2019
Entrez Id: 1666
Gene Symbol: DECR1
DECR1
Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 399 0.426 0.885 4.5E-14 0.010 None 1.000 1 0 2017 2017
Entrez Id: 114112
Gene Symbol: TXNRD3
TXNRD3
Q86VQ6 thioredoxin reductase 3 Enzyme 37 0.653 0.615 8.3E-08 0.010 None 1.000 1 0 2017 2017
Entrez Id: 1583
Gene Symbol: CYP11A1
CYP11A1
P05108 cytochrome P450 family 11 subfamily A member 1 166 0.547 0.731 5.5E-07 0.020 None 0.500 2 0 2015 2019
Entrez Id: 10587
Gene Symbol: TXNRD2
TXNRD2
Q9NNW7 thioredoxin reductase 2 Enzyme 134 0.548 0.731 3.5E-11 0.040 None 0.750 4 0 2014 2019
Entrez Id: 1028
Gene Symbol: CDKN1C
CDKN1C
P49918 cyclin dependent kinase inhibitor 1C 298 0.456 0.846 0.82 0.010 None 1.000 1 0 2014 2014
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.200 None 1.000 1 0 2014 2014
Entrez Id: 23530
Gene Symbol: NNT
NNT
Q13423 nicotinamide nucleotide transhydrogenase Enzyme 88 0.601 0.577 0.97 0.060 None 1.000 6 1 2013 2016
Entrez Id: 4173
Gene Symbol: MCM4
MCM4
P33991 minichromosome maintenance complex component 4 Enzyme 43 0.666 0.654 1.5E-04 0.020 None 1.000 2 0 2013 2013
Entrez Id: 4157
Gene Symbol: MC1R
MC1R
Q01726 melanocortin 1 receptor G-protein coupled receptor 183 0.524 0.808 8.1E-11 0.010 None 1.000 1 0 2012 2012
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 470 0.418 0.885 0.85 0.200 None 1.000 2 0 2011 2012
Entrez Id: 6770
Gene Symbol: STAR
STAR
P49675 steroidogenic acute regulatory protein 177 0.513 0.808 8.8E-11 0.060 None 0.833 6 3 2009 2019
Entrez Id: 8086
Gene Symbol: AAAS
AAAS
Q9NRG9 aladin WD repeat nucleoporin 92 0.601 0.654 2.4E-13 0.010 None 1.000 1 0 2008 2008
Entrez Id: 56246
Gene Symbol: MRAP
MRAP
Q8TCY5 melanocortin 2 receptor accessory protein 51 0.674 0.500 2.1E-03 0.080 None 1.000 8 0 2006 2019
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 0.200 None 1.000 1 0 2004 2004
Entrez Id: 2688
Gene Symbol: GH1
GH1
P01241 growth hormone 1 Signaling 686 0.373 0.923 3.0E-02 0.010 None 1.000 1 0 2004 2004
Entrez Id: 60
Gene Symbol: ACTB
ACTB
P60709 actin beta Cellular structure 1110 0.325 0.923 0.99 0.010 None 1.000 1 0 2001 2001
Entrez Id: 998
Gene Symbol: CDC42
CDC42
P60953 cell division cycle 42 Enzyme modulator 327 0.458 0.846 0.79 0.010 None 1.000 1 0 2001 2001
Entrez Id: 6654
Gene Symbol: SOS1
SOS1
Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 261 0.485 0.808 1.00 0.230 None 1.000 4 0 2000 2017
Entrez Id: 56731
Gene Symbol: SLC2A4RG
SLC2A4RG
Q9NR83 SLC2A4 regulator Transcription factor 66 0.615 0.692 0.22 0.030 None 1.000 3 0 2000 2010
Entrez Id: 5923
Gene Symbol: RASGRF1
RASGRF1
Q13972 Ras protein specific guanine nucleotide releasing factor 1 Enzyme modulator 124 0.537 0.769 1.00 0.030 None 1.000 3 0 2000 2017